Dr. David Caldwell was born in 1799 and came from a wealthy, but pious family. His father was a Presbyterian minister and at least four of David’s siblings followed the family tradition. David on the other hand graduated from The State University in Chapel Hill in 1819, then he attended a series of medical lectures in Philadelphia. In 1820 Dr. Caldwell began practicing medicine in Charlotte with a partner, Dr. McKenzie. They practiced Heroic Medicine, which was typical for the time. It was believed that illness was caused by an excess of the four major fluids of the body; blood, phlegm, bile, and black bile. Treatments were supposed to bring the body back into balance through processes like bleeding or purging. In 1826 David marries Harriet Davidson. Between 1827 and 1844 David & Harriet have eight children, four boys and four girls. The Caldwell’s move into Frew’s old homesite in 1832, at the time the property still belonged to Harriet’s father William Davidson. The next year David purchases the property, by selling a piece of land in Tennessee that Harriet Davidson Caldwell had inherited directly from her late mother. The family lived happily and comfortably for the next dozen years, making money in many different ways on the subsistence farm. In 1844 tragedy struck as an epidemic of erysipelas came through the town. Within a year Dr. Caldwell’s wife, Harriett, and three of their children had died. After his wife’s death he brings in an enslaved woman named Cherry to look after the remaining five children. The Dr. remarries in 1849, his new bride was named Adeline Hutchison and she was a wealthy woman from Rock Hill. Adeline had a deed of trust with Dr. Caldwell stating that the wealth she brought into the relationship should remain hers, and should only be inherited by any children the couple may have. They have one daughter, Addie born in 1851. Caldwell dies on Christmas Eve 1861, shortly after the outbreak of the Civil War. Shortly after his death Caldwell’s two remaining sons enlist in the confederacy and Adeline moves the four girls to Rock Hill and rents out the home during the war.